| Scyler | | |
| Seabert | English | Glory at Sea, Sea Bright, Shining Sea |
| Seabron | | |
| Seabrook | English | From the Brook by the Sea, Brook near the Sea |
| Seadon | English | From the Hill by the Sea |
| Seamas | Hebrew, English | Supplanter, Jimmy, Variant of Jacob, Holds the Hee |
| Seananthony | Hebrew, Latin, Greek | Yahweh is Gracious, God is Merciful, Praiseworthy, |
| Seanchristopher | | |
| Seandell | Celtic, Hebrew, English-American | The Lord is Gracious, Yahweh is Gracious |
| Seandre | | |
| Seanjohn | Hebrew | Yahweh is Gracious, God is Merciful, Gift of God, |
| Seanmatthew | | |
| Seavy | | |
| Seaward | English | Sea Guardian |
| Sebald | Old High German, Germanic, Latin | Victory, Bold, Brave, Warrior, Brotherly, From Ger |
| Sebastean | Old Greek | Man from Sebaste, Which was a City in Asia, Revere |
| Sebastino | | |
| Sebastyen | Old Greek | Man from Sebaste, Which was a City in Asia, Revere |
| Sebastyn | Old Greek | Man from Sebaste, Which was a City in Asia, Revere |
| Sebaztian | Old Greek | Man from Sebaste, Which was a City in Asia, Revere |
| Sebern | | |
| Sebero | | |
| Sebie | | |
| Seburn | | |
| Secca | | |
| Serigo | | |
| Serlo | | |
| Sesario | | |
| Sethan | Hebrew | Appointed One, Placed, The Appointed, (Replacement |
| Sethaniel | | |
| Sethe | Hebrew | Appointed One, Placed, The Appointed, (Replacement |
| Seumas | Hebrew | Yahweh May Protect, Holder of the Heel, Supplanter |
| Sevaughn | | |
| Seveon | | |
| Severen | | |
| Severio | | |
| Severyn | Latin, German, Romanian, Russian, Scandinavian, Slavic | Severe, River in England, Stern, Strict, Restraine |
| Sevion | | |
| Sewall | Old English | Sea Powerful, Sea Ruler |
| Sewerd | English | Sea Guardian |
